Ferritin is a macromolecule with a molecular weight of at least 440 kD (depending on the iron content) and consists of a protein shell (apoferritin) of 24 subunits and an iron core containing an average of approximately 2500 Fe3+ ions (in liver and spleen ferritin).
The determination of ferritin is a suitable method for ascertaining the iron metabolism situation. Determination of ferritin at the beginning of therapy provides a representative measure of the body’s iron reserves.
A storage deficiency in the reticulo-endothelial system (RES) can be detected at a very early stage.